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KMID : 0356919940270091083
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Korean Journal of Anesthesiology
1994 Volume.27 No. 9 p.1083 ~ p.1091
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Effects of Fentanyl, Midazolam, and Fentanyl-Midazolam on the Cardiovascular System and Blood Glucose during General Anesthetic Induction
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임은성
전대근/신효철/신용섭/김혜자/최세진
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Abstract
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In this study, we evaluated the effects of fentanyl, midazolam, and fentanyl-midazolam on cardiovascular system and blood glucose during endotracheal intubation in forty normotensive patients scheduled for elective surgery under general
anesthesia.
The
patients were randomly classified into four groups; GroupⅠ(control) received tracheal intubation with thiopental 5 mg/kg (n=10), groupⅡreceived tracheal intubation with fentanyl 6㎍/kg followed by thiopental 2 mg/kg (n=10), group Ⅲreceived
tracheal
intubation with midazolam 0.3 mg/kg (n=10), group IV received tracheal intubation with fentanyl 4㎍/kg followed by midazolam 1 mg/kg (n=10).
The changes of systolic blood pressure, diastolic blood pressure, mean arterial blood pressure, heart rate, and blood glucose were compared in each group.
@ES The results were as follows:
@EN 1) In group Ⅰ, endotracheal intubation caused a significant rise in SBP, HR and blood glucose.
2) In group Ⅱ, endotracheal intubation caused little changes in SBP, DBP, MAP and blood glucose but HR was rised .
3) In group Ⅲ, endotracheal intubation caused little changes in SBP, DBP, MAP, HR and blood glucose.
4) In group IV, endotracheal intubation caused little changes in SBP, DBP, MAP, HR and blood glucose.
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KEYWORD
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